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Identification of a variant in KDR associated with serum VEGFR2 and pharmacodynamics of pazopanib
PURPOSE: Vascular endothelial growth factor receptor (VEGFR) kinases are important drug targets in oncology that affect function of systemic endothelial cells. To discover genetic markers that affect VEGFR inhibitor pharmacodynamics we performed a genome-wide association study of serum soluble vascu...
Kaydedildi:
| Yayımlandı: | Clin Cancer Res |
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4323272/ https://ncbi.nlm.nih.gov/pubmed/25411163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1683 |
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