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Technical Considerations in the Development of Circulating Peptides as Pharmacodynamic Biomarkers for Angiogenesis Inhibitors
To determine the biological reproducibility and estimate relevant covariates for candidate circulating biomarkers of angiogenesis, we conducted 3 sub-studies with ≤ 15 subjects each. In study 1, 6 healthy subjects provided 13 blood samples across 14–24 days. In study 2, 15 advanced solid tumor patie...
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| Publicado no: | J Clin Pharmacol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4276412/ https://ncbi.nlm.nih.gov/pubmed/24374901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.254 |
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