Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and for growth inhibition of breast cancer cells and cancer stem-like cells

Carriers of germline mutations in the BRCA1 gene have a significant increased lifetime risk for being diagnosed with breast cancer. The incomplete penetrance of BRCA1 suggests that environmental and/or genetic factors modify the risk and incidence among mutation carriers. Nutrition and particular mi...

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Udgivet i:Oncotarget
Main Authors: Pickholtz, Itay, Saadyan, Shira, Keshet, Gilmor I., Wang, Victor S., Cohen, Rachel, Bouwman, Peter, Jonkers, Jos, Byers, Stephen W., Papa, Moshe Z., Yarden, Ronit I.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322975/
https://ncbi.nlm.nih.gov/pubmed/25460500
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