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BRCA1 interacts with components of the histone deacetylase complex

Germ-line mutations in the BRCA1 tumor-suppressor gene are associated with an increased susceptibility to breast and ovarian cancer. BRCA1 contains a carboxyl-terminal domain (BRCT) that is shared with several other proteins involved in maintaining genome integrity. In an effort to understand the fu...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Yarden, Ronit I., Brody, Lawrence C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21803/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10220405/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.9.4983
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