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BRCA1 interacts with components of the histone deacetylase complex

Germ-line mutations in the BRCA1 tumor-suppressor gene are associated with an increased susceptibility to breast and ovarian cancer. BRCA1 contains a carboxyl-terminal domain (BRCT) that is shared with several other proteins involved in maintaining genome integrity. In an effort to understand the fu...

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Autori principali: Yarden, Ronit I., Brody, Lawrence C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC21803/
https://ncbi.nlm.nih.gov/pubmed/10220405
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