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An Agonist of Toll-Like Receptor 5 Has Radioprotective Activity in Mouse and Primate Models
The toxicity of ionizing radiation is associated with massive apoptosis in radiosensitive organs. Here, we investigate whether a drug that activates a signaling mechanism used by tumor cells to suppress apoptosis can protect healthy cells from the harmful effects of radiation. We studied CBLB502, a...
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| Опубликовано в: : | Science |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4322935/ https://ncbi.nlm.nih.gov/pubmed/18403709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1154986 |
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