Oral interleukin-10 alleviates polyposis via neutralization of pathogenic T-regulatory cells

Immune dysregulation drives the pathogenesis of chronic inflammatory, autoimmune and dysplastic disorders. While often intended to address localized pathology, most immune modulatory therapies are administered systemically and carry inherent risk of multi-organ toxicities. Here we demonstrate, in a...

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Vydáno v:Cancer Res
Hlavní autoři: Chung, Allen Y., Li, Qingsheng, Blair, Sarah J., De Jesus, Magdia, Dennis, Kristen L., LeVea, Charles, Yao, Jin, Sun, Yijun, Conway, Thomas F., Virtuoso, Lauren P., Battaglia, Nicholas G., Furtado, Stacia, Mathiowitz, Edith, Mantis, Nicholas J., Khazaie, Khashayarsha, Egilmez, Nejat K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322772/
https://ncbi.nlm.nih.gov/pubmed/25228656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0918
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