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Modulating gut immunity and neoplasia with oral cytokine adjuvants
Oral administration of particulate IL-10 suppressed polyposis, ameliorated systemic pathology and extended lifespan in APC(min/+) mice. Therapeutic effect was associated with selective activity of IL-10 on intestinal CD4+Foxp3+RORγt+IL-17+ pathogenic T-regulatory cells. Studies were recently extende...
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| Publicado en: | Oncoimmunology |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485710/ https://ncbi.nlm.nih.gov/pubmed/26137401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2014.1002724 |
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