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Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening

Mitochondrial production of reactive oxygen species is often considered an unavoidable consequence of aerobic metabolism and currently cannot be manipulated without perturbing oxidative phosphorylation. Antioxidants are widely used to suppress effects of reactive oxygen species after formation, but...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Free Radic Biol Med
Päätekijät: Orr, Adam L., Ashok, Deepthi, Sarantos, Melissa R., Shi, Tong, Hughes, Robert E., Brand, Martin D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321955/
https://ncbi.nlm.nih.gov/pubmed/23994103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.08.170
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