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A novel mechanism of B-cell mediated immune suppression through CD73-expression and adenosine production

Immune suppression by regulatory T (Treg) cells and regulatory B (Breg) cells is a critical mechanism to limit excess inflammation and autoimmunity. IL-10 is considered to be the major mediator of B cell-induced immune suppression. Here, we report a novel mechanism for immune suppression through ade...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Kaku, Hiroaki, Cheng, Kai Fan, Al-Abed, Yousef, Rothstein, Thomas L.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321875/
https://ncbi.nlm.nih.gov/pubmed/25392527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400336
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