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CD73-adenosine reduces immune responses and survival in ovarian cancer patients

Multiple non-redundant immunosuppressive pathways are active within the microenvironment of cancers to avoid tumor eradication by the immune system. Our results demonstrate that the CD73-adenosine pathway is a major immunosuppressive mechanism co-opted by ovarian tumors to escape antitumor immunity....

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Pubblicato in:Oncoimmunology
Autori principali: Gaudreau, Pierre-Olivier, Allard, Bertrand, Turcotte, Martin, Stagg, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910753/
https://ncbi.nlm.nih.gov/pubmed/27467942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1127496
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