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Reconstruction of the protein architecture of the budding yeast kinetochore-microtubule attachment using FRET

BACKGROUND: The kinetochore is a multiprotein machine that couples chromosome movement to microtubule (MT) polymerization and depolymerization. It uses numerous copies of at least three MT-binding proteins to generate bidirectional movement. The nanoscale organization of these proteins within the ki...

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Publicat a:Curr Biol
Autors principals: Aravamudhan, Pavithra, Felzer-Kim, Isabella, Gurunathan, Kaushik, Joglekar, Ajit P.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320969/
https://ncbi.nlm.nih.gov/pubmed/24930965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.05.014
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