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Stu2 acts as a microtubule destabilizer in metaphase budding yeast spindles

The microtubule-associated protein Stu2 (XMAP215) has the remarkable ability to act either as a polymerase or as a destabilizer of the microtubule plus end. In budding yeast, it is required for the dynamicity of spindle microtubules and also for kinetochore force generation. To understand how Stu2 c...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Humphrey, Lauren, Felzer-Kim, Isabella, Joglekar, Ajit P.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996951/
https://ncbi.nlm.nih.gov/pubmed/29187578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-08-0494
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