Aberrant DNA Damage Response Pathways May Predict the Outcome of Platinum Chemotherapy in Ovarian Cancer

Ovarian carcinoma (OC) is the most lethal gynecological malignancy. Despite the advances in the treatment of OC with combinatorial regimens, including surgery and platinum-based chemotherapy, patients generally exhibit poor prognosis due to high chemotherapy resistance. Herein, we tested the hypothe...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Stefanou, Dimitra T., Bamias, Aristotelis, Episkopou, Hara, Kyrtopoulos, Soterios A., Likka, Maria, Kalampokas, Theodore, Photiou, Stylianos, Gavalas, Nikos, Sfikakis, Petros P., Dimopoulos, Meletios A., Souliotis, Vassilis L.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320060/
https://ncbi.nlm.nih.gov/pubmed/25659114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117654
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