Clinical Perspectives of ERCC1 in Bladder Cancer

ERCC1 is a key regulator of nucleotide excision repair (NER) pathway that repairs bulky DNA adducts, including intrastrand DNA adducts and interstrand crosslinks (ICLs). Overexpression of ERCC1 has been linked to increased DNA repair capacity and platinum resistance in solid tumors. Multiple single...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Koutsoukos, Konstantinos, Andrikopoulou, Angeliki, Dedes, Nikos, Zagouri, Flora, Bamias, Aristotelis, Dimopoulos, Meletios-Athanasios
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700570/
https://ncbi.nlm.nih.gov/pubmed/33266377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228829
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