Clinical Perspectives of ERCC1 in Bladder Cancer

ERCC1 is a key regulator of nucleotide excision repair (NER) pathway that repairs bulky DNA adducts, including intrastrand DNA adducts and interstrand crosslinks (ICLs). Overexpression of ERCC1 has been linked to increased DNA repair capacity and platinum resistance in solid tumors. Multiple single...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Koutsoukos, Konstantinos, Andrikopoulou, Angeliki, Dedes, Nikos, Zagouri, Flora, Bamias, Aristotelis, Dimopoulos, Meletios-Athanasios
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Review
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700570/
https://ncbi.nlm.nih.gov/pubmed/33266377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228829
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