Clinical Perspectives of ERCC1 in Bladder Cancer

ERCC1 is a key regulator of nucleotide excision repair (NER) pathway that repairs bulky DNA adducts, including intrastrand DNA adducts and interstrand crosslinks (ICLs). Overexpression of ERCC1 has been linked to increased DNA repair capacity and platinum resistance in solid tumors. Multiple single...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Koutsoukos, Konstantinos, Andrikopoulou, Angeliki, Dedes, Nikos, Zagouri, Flora, Bamias, Aristotelis, Dimopoulos, Meletios-Athanasios
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700570/
https://ncbi.nlm.nih.gov/pubmed/33266377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228829
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