Aberrant DNA Damage Response Pathways May Predict the Outcome of Platinum Chemotherapy in Ovarian Cancer

Ovarian carcinoma (OC) is the most lethal gynecological malignancy. Despite the advances in the treatment of OC with combinatorial regimens, including surgery and platinum-based chemotherapy, patients generally exhibit poor prognosis due to high chemotherapy resistance. Herein, we tested the hypothe...

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Udgivet i:PLoS One
Main Authors: Stefanou, Dimitra T., Bamias, Aristotelis, Episkopou, Hara, Kyrtopoulos, Soterios A., Likka, Maria, Kalampokas, Theodore, Photiou, Stylianos, Gavalas, Nikos, Sfikakis, Petros P., Dimopoulos, Meletios A., Souliotis, Vassilis L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320060/
https://ncbi.nlm.nih.gov/pubmed/25659114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117654
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