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Transcription Driven Somatic DNA Methylation within the Imprinted Gnas Cluster

Differential marking of genes in female and male gametes by DNA methylation is essential to genomic imprinting. In female gametes transcription traversing differentially methylated regions (DMRs) is a common requirement for de novo methylation at DMRs. At the imprinted Gnas cluster oocyte specific t...

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Veröffentlicht in:PLoS One
Hauptverfasser: Mehta, Stuti, Williamson, Christine M., Ball, Simon, Tibbit, Charlotte, Beechey, Colin, Fray, Martin, Peters, Jo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319783/
https://ncbi.nlm.nih.gov/pubmed/25659103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117378
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