Transcription Driven Somatic DNA Methylation within the Imprinted Gnas Cluster

Differential marking of genes in female and male gametes by DNA methylation is essential to genomic imprinting. In female gametes transcription traversing differentially methylated regions (DMRs) is a common requirement for de novo methylation at DMRs. At the imprinted Gnas cluster oocyte specific t...

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Publicat a:PLoS One
Autors principals: Mehta, Stuti, Williamson, Christine M., Ball, Simon, Tibbit, Charlotte, Beechey, Colin, Fray, Martin, Peters, Jo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319783/
https://ncbi.nlm.nih.gov/pubmed/25659103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117378
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