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Transcription Driven Somatic DNA Methylation within the Imprinted Gnas Cluster

Differential marking of genes in female and male gametes by DNA methylation is essential to genomic imprinting. In female gametes transcription traversing differentially methylated regions (DMRs) is a common requirement for de novo methylation at DMRs. At the imprinted Gnas cluster oocyte specific t...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Mehta, Stuti, Williamson, Christine M., Ball, Simon, Tibbit, Charlotte, Beechey, Colin, Fray, Martin, Peters, Jo
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319783/
https://ncbi.nlm.nih.gov/pubmed/25659103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117378
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