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Bayesian hierarchical modeling of patient subpopulations: Efficient designs of Phase II oncology clinical trials

BACKGROUND: In oncology, the treatment paradigm is shifting toward personalized medicine, where the goal is to match patients to the treatments most likely to deliver benefit. Treatment effects in various subpopulations may provide some information about treatment effects in other subpopulations. PU...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Trials
Prif Awduron: Berry, Scott M, Broglio, Kristine R, Groshen, Susan, Berry, Donald A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319656/
https://ncbi.nlm.nih.gov/pubmed/23983156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774513497539
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