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Clinically relevant fluoroquinolone resistance due to constitutive overexpression of the PatAB ABC transporter in Streptococcus pneumoniae is conferred by disruption of a transcriptional attenuator
OBJECTIVES: Constitutive overexpression of patAB has been observed in several unrelated fluoroquinolone-resistant laboratory mutants and clinical isolates; therefore, we sought to identify the cause of this overexpression. METHODS: Constitutive patAB overexpression in two clinical isolates and a lab...
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| Pubblicato in: | J Antimicrob Chemother |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319486/ https://ncbi.nlm.nih.gov/pubmed/25411187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku449 |
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