The Efflux Pump Inhibitor Reserpine Selects Multidrug-Resistant Streptococcus pneumoniae Strains That Overexpress the ABC Transporters PatA and PatB

One way to combat multidrug-resistant microorganisms is the use of efflux pump inhibitors (EPIs). Spontaneous mutants resistant to the EPI reserpine selected from Streptococcus pneumoniae NCTC 7465 and R6 at a frequency suggestive of a single mutational event were also multidrug resistant. No mutati...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Garvey, Mark I., Piddock, Laura J. V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2008
Gaiak:
Mechanisms of Resistance
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346654/
https://ncbi.nlm.nih.gov/pubmed/18362193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01644-07
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