Involvement of the Putative ATP-Dependent Efflux Proteins PatA and PatB in Fluoroquinolone Resistance of a Multidrug-Resistant Mutant of Streptococcus pneumoniae

The multidrug-resistant mutant Streptococcus pneumoniae M22 constitutively overexpresses two genes (patA and patB) that encode proteins homologous to known efflux proteins belonging to the ABC transporter family. It is shown here that PatA and PatB were strongly induced by quinolone antibiotics and...

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Bibliographic Details
Main Authors: Marrer, Estelle, Schad, Karen, Satoh, Andreas T., Page, Malcolm G. P., Johnson, Maggie M., Piddock, Laura J. V.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366865/
https://ncbi.nlm.nih.gov/pubmed/16436727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.2.685-693.2006
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