Involvement of the Putative ATP-Dependent Efflux Proteins PatA and PatB in Fluoroquinolone Resistance of a Multidrug-Resistant Mutant of Streptococcus pneumoniae

The multidrug-resistant mutant Streptococcus pneumoniae M22 constitutively overexpresses two genes (patA and patB) that encode proteins homologous to known efflux proteins belonging to the ABC transporter family. It is shown here that PatA and PatB were strongly induced by quinolone antibiotics and...

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Detalhes bibliográficos
Main Authors: Marrer, Estelle, Schad, Karen, Satoh, Andreas T., Page, Malcolm G. P., Johnson, Maggie M., Piddock, Laura J. V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366865/
https://ncbi.nlm.nih.gov/pubmed/16436727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.2.685-693.2006
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