Identification of a new dysfunctional platelet P2Y(12) receptor variant associated with bleeding diathesis

Defects of the platelet P2Y(12) receptor (P2Y(12)R) for adenosine diphosphate (ADP) are associated with increased bleeding risk. The study of molecular abnormalities associated with inherited qualitative defects of the P2Y(12)R protein is useful to unravel structure-function relationships of the rec...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Lecchi, Anna, Razzari, Cristina, Paoletta, Silvia, Dupuis, Arnaud, Nakamura, Lea, Ohlmann, Philippe, Gachet, Christian, Jacobson, Kenneth A., Zieger, Barbara, Cattaneo, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319231/
https://ncbi.nlm.nih.gov/pubmed/25428217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-517896
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