Identification of a new dysfunctional platelet P2Y(12) receptor variant associated with bleeding diathesis

Defects of the platelet P2Y(12) receptor (P2Y(12)R) for adenosine diphosphate (ADP) are associated with increased bleeding risk. The study of molecular abnormalities associated with inherited qualitative defects of the P2Y(12)R protein is useful to unravel structure-function relationships of the rec...

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Publicat a:Blood
Autors principals: Lecchi, Anna, Razzari, Cristina, Paoletta, Silvia, Dupuis, Arnaud, Nakamura, Lea, Ohlmann, Philippe, Gachet, Christian, Jacobson, Kenneth A., Zieger, Barbara, Cattaneo, Marco
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2015
Matèries:
Platelets and Thrombopoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319231/
https://ncbi.nlm.nih.gov/pubmed/25428217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-517896
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