Identification of a new dysfunctional platelet P2Y(12) receptor variant associated with bleeding diathesis

Defects of the platelet P2Y(12) receptor (P2Y(12)R) for adenosine diphosphate (ADP) are associated with increased bleeding risk. The study of molecular abnormalities associated with inherited qualitative defects of the P2Y(12)R protein is useful to unravel structure-function relationships of the rec...

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Publicado en:Blood
Autores principales: Lecchi, Anna, Razzari, Cristina, Paoletta, Silvia, Dupuis, Arnaud, Nakamura, Lea, Ohlmann, Philippe, Gachet, Christian, Jacobson, Kenneth A., Zieger, Barbara, Cattaneo, Marco
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2015
Materias:
Platelets and Thrombopoiesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319231/
https://ncbi.nlm.nih.gov/pubmed/25428217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-517896
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