Recombinant adeno-associated virus-mediated gene delivery of long chain acyl coenzyme A dehydrogenase (LCAD) into LCAD-deficient mice

BACKGROUND: Very long chain acyl coenzyme A (CoA) dehydrogenase (VLCAD) deficiency is a relatively common mitochondrial β-oxidation disorder. The most severe form of VLCAD deficiency presents with neonatal cardiomyopathy and hepatic failure and is generally fatal within the first year of life. Mice...

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Detalhes bibliográficos
Publicado no:J Gene Med
Main Authors: Beattie, Stuart G., Goetzman, Eric, Tang, Qiuishi, Conlon, Thomas, Campbell-Thompson, Martha, Matern, Dietrich, Vockley, Jerry, Flotte, Terence R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319113/
https://ncbi.nlm.nih.gov/pubmed/18720429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.1242
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