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Establishment and Characterization of Novel Human Primary and Metastatic Anaplastic Thyroid Cancer Cell Lines and Their Genomic Evolution Over a Year as a Primagraft

CONTEXT: Anaplastic thyroid cancer (ATC) has no effective treatment, resulting in a high rate of mortality. We established cell lines from a primary ATC and its lymph node metastasis, and investigated the molecular factors and genomic changes associated with tumor growth. OBJECTIVE: The aim of the s...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Garg, Manoj, Okamoto, Ryoko, Nagata, Yasunobu, Kanojia, Deepika, Venkatesan, Subhashree, M. T., Anand, Braunstein, Glenn D., Said, Jonathan W., Doan, Ngan B., Ho, Quoc, Akagi, Tadayuki, Gery, Sigal, Liu, Li-zhen, Tan, Kar Tong, Chng, Wee Joo, Yang, Henry, Ogawa, Seishi, Koeffler, H. Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318896/
https://ncbi.nlm.nih.gov/pubmed/25365311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-2359
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