Inecalcitol, an analog of 1α,25(OH)(2)D(3), induces growth arrest of androgen-dependent prostate cancer cells

19-nor-14-epi-23-yne-1,25(OH)(2)D(3) (inecalcitol) is a unique vitamin D(3) analog. We evaluated theactivity of inecalcitol in a human prostate cancer model system. The analog was 11-fold more potent than 1,25(OH)(2)D(3) in causing 50% clonal growth inhibition of androgen-sensitive human prostate ca...

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Detalhes bibliográficos
Main Authors: Okamoto, Ryoko, Delansorne, Remi, Wakimoto, Naoki, Doan, Ngan B., Akagi, Tadayuki, Shen, Michelle, Ho, Quoc H., Said, Jonathan W., Koeffler, H. Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288172/
https://ncbi.nlm.nih.gov/pubmed/21732345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.26279
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