In Vivo Deficiency of Both C/EBPβ and C/EBPε Results in Highly Defective Myeloid Differentiation and Lack of Cytokine Response

The CCAAT/enhancer binding proteins (C/EBPs) are transcription factors involved in hematopoietic cell development and induction of several inflammatory mediators. Here, we generated C/EBPβ and C/EBPε double-knockout (bbee) mice and compared their phenotypes to those of single deficient (bbEE and BBe...

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Main Authors: Akagi, Tadayuki, Thoennissen, Nils H., George, Ann, Crooks, Gay, Song, Jee Hoon, Okamoto, Ryoko, Nowak, Daniel, Gombart, Adrian F., Koeffler, H. Phillip
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972224/
https://ncbi.nlm.nih.gov/pubmed/21072215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015419
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