Impaired response to GM-CSF and G-CSF, and enhanced apoptosis in C/EBPβ-deficient hematopoietic cells

Transcription factors known as CCAAT enhancer binding proteins (C/EBPs) are involved in hematopoietic differentiation, including myelopoiesis and granulopoiesis. C/EBPβ-deficient mice develop normally; however, they exhibit defective macrophage function, resulting in increased susceptibility to infe...

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Detalhes bibliográficos
Main Authors: Akagi, Tadayuki, Saitoh, Takayuki, O'Kelly, James, Akira, Shizuo, Gombart, Adrian F., Koeffler, H. Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265449/
https://ncbi.nlm.nih.gov/pubmed/18056834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-04-087213
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