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Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis
In vitro studies indicate that Cul4A ubiquitin ligases target for ubiquitin-mediated proteolysis regulators of cell-cycle progression, apoptosis, development, and DNA repair. In hematopoietic cell lines, studies by our group and others showed that Cul4A ligases regulate proliferation and differentia...
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| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society of Hematology
2008
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442743/ https://ncbi.nlm.nih.gov/pubmed/18339895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-126300 |
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