Off Target Effects of c-MET Inhibitors on Thyroid Cancer Cells

Aberrantly activated c-MET signaling occurs in several cancers, promoting the development of c-MET inhibitors. In this study, we found that eight of 8 thyroid cancer cell lines (including six anaplastic thyroid cell lines) have prominent expression of c-MET protein. Fifty percent of the thyroid canc...

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Detalhes bibliográficos
Main Authors: Zhou, Yan, Zhao, Conghui, Gery, Sigal, Braunstein, Glenn D., Okamoto, Ryoko, Alvarez, Rocio, Miles, Steven A., Doan, Ngan B., Said, Jonathan W., Gu, Jiang, Koeffler, H. Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947168/
https://ncbi.nlm.nih.gov/pubmed/24170771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0187
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