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Belinostat and panobinostat (HDACI): in vitro and in vivo studies in thyroid cancer

PURPOSE: Advanced thyroid cancer responds poorly to most therapies. New therapies and combinations are needed. The aim of this study was to examine both in vitro and in vivo activity of two relatively new histone deacetylase inhibitors (HDACIs), belinostat and panobinostat, and a variety of tyrosine...

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Bibliografiske detaljer
Main Authors: Chan, Daniel, Zheng, Yun, Tyner, Jeffrey W., Chng, Wee Joo, Chien, Wen Wen, Gery, Sigal, Leong, Geraldine, Braunstein, Glenn D., Koeffler, H. Phillip
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742422/
https://ncbi.nlm.nih.gov/pubmed/23824064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-013-1465-6
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