Belinostat and panobinostat (HDACI): in vitro and in vivo studies in thyroid cancer

PURPOSE: Advanced thyroid cancer responds poorly to most therapies. New therapies and combinations are needed. The aim of this study was to examine both in vitro and in vivo activity of two relatively new histone deacetylase inhibitors (HDACIs), belinostat and panobinostat, and a variety of tyrosine...

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Main Authors: Chan, Daniel, Zheng, Yun, Tyner, Jeffrey W., Chng, Wee Joo, Chien, Wen Wen, Gery, Sigal, Leong, Geraldine, Braunstein, Glenn D., Koeffler, H. Phillip
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2013
Teme:
Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742422/
https://ncbi.nlm.nih.gov/pubmed/23824064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-013-1465-6
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