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Actions of the Small Molecule Ligands SW106 and AH-3960 on the Type-1 Parathyroid Hormone Receptor

The parathyroid hormone receptor-1 (PTHR1) plays critical roles in regulating blood calcium levels and bone metabolism and is thus of interest for small-molecule ligand development. Of the few small-molecule ligands reported for the PTHR1, most are of low affinity, and none has a well-defined mechan...

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Détails bibliographiques
Publié dans:Mol Endocrinol
Auteurs principaux: Carter, Percy H., Dean, Thomas, Bhayana, Brijesh, Khatri, Ashok, Rajur, Raj, Gardella, Thomas J.
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318877/
https://ncbi.nlm.nih.gov/pubmed/25584411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1129
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