Phosphatidylinositol 3-Kinase–Independent Signaling Pathways Contribute to ICOS-Mediated T Cell Costimulation in Acute Graft-Versus-Host Disease in Mice

We and others have previously shown that ICOS plays an important role in inducing acute graft-versus-host disease (GVHD) in murine models of allogeneic bone marrow transplantation. ICOS potentiates TCR-mediated PI3K activation and intracellular calcium mobilization. However, ICOS signal transduction...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Immunol
Hlavní autoři: Li, Jun, Heinrichs, Jessica, Leconte, Julien, Haarberg, Kelley, Semple, Kenrick, Liu, Chen, Gigoux, Mathieu, Kornete, Mara, Piccirillo, Ciriaco A., Suh, Woong-Kyung, Yu, Xue-Zhong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318500/
https://ncbi.nlm.nih.gov/pubmed/23729441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203485
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky