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Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase
The T-cell costimulatory receptors, CD28 and the inducible costimulator (ICOS), are required for the generation of follicular B helper T cells (T(FH)) and germinal center (GC) reaction. A common signal transducer used by CD28 and ICOS is the phosphoinositide 3-kinase (PI3K). Although it is known tha...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787139/ https://ncbi.nlm.nih.gov/pubmed/19915142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911573106 |
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