Anti-Chlamydial Th17 Responses Are Controlled by the Inducible Costimulator Partially through Phosphoinositide 3-Kinase Signaling

We previously showed that mice deficient in the Inducible Costimulator ligand (ICOSL-KO) develop more severe disease and lung pathology with delayed bacterial clearance upon respiratory infection of Chlamydia muridarum. Importantly, the exacerbation of disease in ICOSL-KO mice was seen despite heigh...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Gao, Xiaoling, Gigoux, Mathieu, Yang, Jie, Leconte, Julien, Yang, Xi, Suh, Woong-Kyung
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527575/
https://ncbi.nlm.nih.gov/pubmed/23285133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052657
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