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Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5
Binding of the Hedgehog (Hh) protein signal to its receptor, Patched, induces accumulation of the seven-pass transmembrane protein Smoothened (Smo) within the primary cilium and of the zinc finger transcription factor Gli2 at the ciliary tip, resulting ultimately in Gli-mediated changes in nuclear g...
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| Publicado no: | Genes Dev |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4318143/ https://ncbi.nlm.nih.gov/pubmed/25644602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.252676.114 |
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