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Preparation and characterization of anti-tissue factor single-chain variable fragment antibody for cancer diagnosis

Tissue factor (TF), which serves as the initiator of the extrinsic blood coagulation cascade, has been found to be overexpressed in various solid tumors, especially brain tumors, pancreatic cancer, and gastric cancer. Overexpression of TF is considered to contribute to the high incidence of thrombot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Sci
Hauptverfasser: Sato, Ryuta, Obonai, Toshifumi, Tsumura, Ryo, Tsumoto, Kouhei, Koga, Yoshikatsu, Yasunaga, Masahiro, Matsumura, Yasuhiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317963/
https://ncbi.nlm.nih.gov/pubmed/25311092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12557
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