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Phase I study of olaratumab in Japanese patients with advanced solid tumors

Olaratumab (IMC-3G3) is a fully human IgG1 monoclonal antibody that selectively binds the external domain of human platelet-derived growth factor receptor-α with high affinity and blocks ligand binding. This was a single-center, dose-escalation, phase I trial of olaratumab in Japanese patients with...

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Dades bibliogràfiques
Publicat a:Cancer Sci
Autors principals: Doi, Toshihiko, Ma, Yan, Dontabhaktuni, Aruna, Nippgen, Cornelia, Nippgen, Johannes, Ohtsu, Atsushi
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317910/
https://ncbi.nlm.nih.gov/pubmed/24816152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12444
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