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Phase I study of olaratumab in Japanese patients with advanced solid tumors
Olaratumab (IMC-3G3) is a fully human IgG1 monoclonal antibody that selectively binds the external domain of human platelet-derived growth factor receptor-α with high affinity and blocks ligand binding. This was a single-center, dose-escalation, phase I trial of olaratumab in Japanese patients with...
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Publicat a: | Cancer Sci |
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Autors principals: | , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Blackwell Publishing Ltd
2014
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4317910/ https://ncbi.nlm.nih.gov/pubmed/24816152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12444 |
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