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Competition between Primary Nucleation and Autocatalysis in Amyloid Fibril Self-Assembly
Kinetic measurements of the self-assembly of proteins into amyloid fibrils are often used to make inferences about molecular mechanisms. In particular, the lag time—the quiescent period before aggregates are detected—is often found to scale with the protein concentration as a power law, whose expone...
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| Veröffentlicht in: | Biophys J |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4317560/ https://ncbi.nlm.nih.gov/pubmed/25650930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.11.3465 |
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