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p53 Degradation by a Coronavirus Papain-like Protease Suppresses Type I Interferon Signaling
Infection by human coronaviruses is usually characterized by rampant viral replication and severe immunopathology in host cells. Recently, the coronavirus papain-like proteases (PLPs) have been identified as suppressors of the innate immune response. However, the molecular mechanism of this inhibiti...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4317044/ https://ncbi.nlm.nih.gov/pubmed/25505178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.619890 |
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