The papain-like protease of porcine epidemic diarrhea virus negatively regulates type I interferon pathway by acting as a viral deubiquitinase

Porcine epidemic diarrhea virus (PEDV) is the cause of an economically important swine disease. Previous studies suggested that PEDV does not elicit a robust IFN response, but the mechanism(s) used to evade or block this innate immune response was not known. In this study, we found that PEDV infecti...

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Dettagli Bibliografici
Pubblicato in:J Gen Virol
Autori principali: Xing, Yaling, Chen, Jianfei, Tu, Jian, Zhang, Bailing, Chen, Xiaojuan, Shi, Hongyan, Baker, Susan C., Feng, Li, Chen, Zhongbin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for General Microbiology 2013
Soggetti:
Animal
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811637/
https://ncbi.nlm.nih.gov/pubmed/23596270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.051169-0
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