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Comprehensive Sieve Analysis of Breakthrough HIV-1 Sequences in the RV144 Vaccine Efficacy Trial
The RV144 clinical trial showed the partial efficacy of a vaccine regimen with an estimated vaccine efficacy (VE) of 31% for protecting low-risk Thai volunteers against acquisition of HIV-1. The impact of vaccine-induced immune responses can be investigated through sieve analysis of HIV-1 breakthrou...
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| Gepubliceerd in: | PLoS Comput Biol |
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| Hoofdauteurs: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4315437/ https://ncbi.nlm.nih.gov/pubmed/25646817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003973 |
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