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Tryptophan-Degrading Enzymes in Tumoral Immune Resistance
Tryptophan is required for T lymphocyte effector functions. Its degradation is one of the mechanisms selected by tumors to resist immune destruction. Two enzymes, tryptophan-2,3-dioxygenase and indoleamine 2,3-dioxygenase 1, control tryptophan degradation through the kynurenine pathway. A third prot...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4315104/ https://ncbi.nlm.nih.gov/pubmed/25691885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00034 |
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