Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

Tryptophan catabolism mediated by indoleamine 2,3-dioxygenase (IDO1) is an important mechanism of peripheral immune tolerance contributing to tumoral immune resistance, and IDO1 inhibition is an active area of drug development. Tryptophan 2,3-dioxygenase (TDO) is an unrelated hepatic enzyme that als...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Pilotte, Luc, Larrieu, Pierre, Stroobant, Vincent, Colau, Didier, Dolušić, Eduard, Frédérick, Raphaël, De Plaen, Etienne, Uyttenhove, Catherine, Wouters, Johan, Masereel, Bernard, Van den Eynde, Benoît J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2012
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289319/
https://ncbi.nlm.nih.gov/pubmed/22308364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113873109
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы