Tryptophan 2,3-Dioxygenase Expression Identified in Murine Decidual Stromal Cells Is Not Essential for Feto-Maternal Tolerance

Indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO) catalyze the rate-limiting step of tryptophan catabolism along the kynurenine pathway, which has important immuno suppressive properties, particularly in tumor cells and dendritic cells. The prominent expression of IDO1 in the...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Hoffmann, Delia, Dvorakova, Tereza, Schramme, Florence, Stroobant, Vincent, Van den Eynde, Benoit J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752949/
https://ncbi.nlm.nih.gov/pubmed/33363543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.601759
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